Articles> Focus on Fertility (cont.)

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A study presented by Dr. M.R. Safarinejad at a previous ICQA conference highlighted the role of ubiquinol in subjects with male infertility, and was later published in a 2012 peerreviewed publication The Journal of Urology. In a double-blind, placebocontrolled, randomized, clinical trial over a 26-week treatment period, Safarinejad investigated male infertility in a total of 228 men. Subjects in the study had the male infertility condition known as idiopathic oligoasthenoteratozoospermia (OAT), which is marked by poor semen quality criteria with less than 14 percent normal forms, oligozoospermia by a sperm concentration of less than 20 X 106 spermatozoa per mL and asthenozoospermia by less than 50 percent of motile spermatozoa with forward progression (according to World Health Organization criteria). The results of the study demonstrated that 200 mg of ubiquinol supplementation per day significantly improved sperm strict morphology, sperm density and sperm motility (see Table above). Safarinejad pointed out that oxidative stress (OS) is a primary influencing factor for male infertility, and he also reaffirmed other scientists’ findings that OS causes a decline in body ubiquinol-to-ubiquinone ratio. Another fertility study presented at the ICQA offered a similar, positive outcome. Dr. A.S.Thakur of the Jagdalpur College in India investigated the ubiquinol supplementation on 20 male subjects with reduced fertility status (subjects were between 20 and 40 years old). After four months of supplementation with 150 mg ubiquinol per day, the total sperm count increased by 53 percent and the total sperm mobility improved by 26 percent. In further analysis of the mobility, the quantity of rapidly motile sperm (RMS) increased 41 percent, while the number of sluggish motile sperm (SMS) decreased 29 percent. In this study, the scientists hypothesized that the favorable findings could be attributed to ubiquinol’s protection of testicular cells against oxidative stress, a theory in line with Safarinejad’s recently published study.